Mi Zhang and Xing Gao, report the discovery of a possible nova (mag approximately 20.1) on several 300-s survey image (limiting mag about 20.5) taken by Xing Gao at Xingming Observatory #3 (N88) around Nov. 21.96229 UTC using a unfiltered CCD (+ 0.6-m f/8 Ritchey-Chretien telescope). The transient approximately located at R.A.=09h55m40.41s +69d03’24”.3 (equinox 2000.0). Which is about 38.8″ east and 30.8″ south of the center of the M81. Nothing is visible at this position on archival images taken on Nov. 16.80679 (limiting mag 20.5) . Images can be found at: http://xjltp.china-vo.org/xm46mz.html